Nanoscale magnetic resonance imaging (NanoMRI) is an active area of applied research with potential applications in structural biology and quantum engineering. The success of this technological vision hinges on improving the instrument's sensitivity and functionality. A particular challenge is the optimization of the magnetic field gradient required for spatial encoding and of the radio frequency field used for spin control, in analogy to the components used in clinical MRI.
View Article and Find Full Text PDFThe one-pot synthesis of antimicrobial bottle brush copolymers is presented. Reversible addition-fragmentation chain-transfer (RAFT) polymerization is used for the production of the polymeric backbone, as well as for the grafts, which were installed using a grafting-from approach. A combination of -isopropyl acrylamide and a Boc-protected primary amine-containing acrylamide was used in different compositions.
View Article and Find Full Text PDFexplore the legal implications of using artificial intelligence in the response to covid-19 and call for more robust evaluation frameworks
View Article and Find Full Text PDFGlucagon-like peptide 1 (GLP-1) receptor agonists are popular antidiabetic drugs with potent glucose-lowering effects and low risk of hypoglycemia. Animal experiments and human data indicate that tolerance develops toward at least some of their effects, e.g.
View Article and Find Full Text PDFMagnetic resonance force microscopy (MRFM) is a scanning probe technique capable of detecting MRI signals from nanoscale sample volumes, providing a paradigm-changing potential for structural biology and medical research. Thus far, however, experiments have not reached sufficient spatial resolution for retrieving meaningful structural information from samples. In this work, we report MRFM imaging scans demonstrating a resolution of 0.
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