Publications by authors named "M E Janssen"
Improving the accUracy of Referrals to the emerGency departmEnt of patieNts with chesT pain using the modified HEART score in Emergency Medical Transport (URGENT 2.0): protocol for a multicentre randomised controlled trial.
BMJ Open
December 2024
Introduction: Ischaemic heart disease is the single most common cause of death worldwide. Traditionally, distinguishing patients with cardiac ischaemia from patients with less alarming disease, in prehospital triage of chest pain, is challenging for both general practitioners and ambulance paramedics. Less than 20% of patients with chest pain, transferred to the emergency department (ED), have an acute coronary syndrome (ACS) and the transportation and analysis at the ED of non-ACS patients result in substantial healthcare costs and a great patient burden.
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- Total knee arthroplasty (TKA) is commonly used for end-stage osteoarthritis, creating a rising healthcare burden that could intensify with an increasing number of surgeries.
- A state-transition model was crafted to analyze the effectiveness and costs of five hypothetical interventions aimed at reducing TKA needs, focusing on areas like avoiding surgeries and improving patient satisfaction.
- Findings revealed significant cost savings associated with interventions that prevent TKAs and revisions, particularly benefiting younger patients, highlighting potential innovations that could maximize the value of care while reducing the reliance on surgical procedures.
Background: This study aimed to explore the feasibility, safety and efficacy of a Modified Atkins Diet (MAD) in patients with mitochondrial myopathy (MM).
Methods: Patients with genetically proven mitochondrial disorder and exercise intolerance or muscle weakness followed a twelve week MAD. Feasibility was measured by diet duration and ketone levels.
Aim: The objective of this study was to compare the detection rates of [F]PSMA-1007 and [F]Fluciclovine in early biochemical recurrence (BCR) of prostate cancer, i.e. with low prostate-specific antigen (PSA) levels (0.
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