Usefulness of immature platelet fraction measurement in predicting hematologic recovery in patients with acute leukemias undergoing high-intensity chemotherapy and stem cell transplantation.

Background And Objectives: The immature platelet fraction (IPF) count is a parameter that quantifies young and reticulated platelets in peripheral blood, which reflects platelet production in the bone marrow. It has been used as a predictive model for bone marrow recovery in patients with acute leukemia after high-intensity chemotherapy and/or stem cell transplantation. This study aimed to evaluate IPF as a predictor of hematologic recovery in these patients.

Radiotherapy Quality Assurance in the SCOPE2 Trial: What Lessons can be Learned for the Next UK Trial in Oesophageal Cancer?

Aims: The SCOPE2 trial evaluates radiotherapy (RT) dose escalation for oesophageal cancer. We report findings from the accompanying RT quality assurance (RTQA) programme and identify recommendations for PROTIEUS, the next UK trial in oesophageal RT.

Maetrials And Methods: SCOPE2's RTQA programme consisted of a pre-accrual and on-trial component.

Cutaneous disorders in captive psittacines, a retrospective study of 1454 cases at a university veterinary teaching hospital (1988-2021).

Background: Psittacines (parrots and their allies) are kept under human care as companion animals, live exhibit specimens in zoological institutions and occasionally as research subjects. Cutaneous disorders such as feather destructive behaviour (FDB) and pododermatitis are commonly noted in clinical reviews, case reports and text book chapters.

Hypothesis/objectives: To document the type, signalment associations and prevalence of cutaneous disorders in a large number of captive psittacines in an academic referral teaching hospital population.

Chlamydial infections in free-ranging raptors presenting to a university veterinary medical teaching hospital (1993-2022).

Objective: To describe the prevalence, clinical findings, lesions, and risk factors associated with chlamydial infections in free-ranging raptors presented to a university veterinary medical teaching hospital.

Methods: Medical records retrospectively searched for raptors admitted from January 1993 through April 2022 were tested for Chlamydia spp infections using quantitative PCR (qPCR), immunohistochemistry, culture, and sequencing. Findings were collected and analyzed.