Publications by authors named "M E Haverkort"
Cost-effectiveness of a nurse-led sexual rehabilitation intervention for women treated with radiotherapy for gynaecological cancer in a randomized trial.
Radiother Oncol
December 2024
Purpose: To compare the cost-effectiveness of a nurse-led sexual rehabilitation intervention with standard care in women treated with external beam radiotherapy, with or without brachytherapy, for gynaecological cancers.
Methods: Eligible women were randomly assigned to the intervention (n = 112) or standard care (n = 117). Primary endpoint was sexual functioning at 12-months post-radiotherapy, assessed by the Female Sexual Function Index (FSFI).
Of the 4 molecular subtypes of endometrial cancer (EC), p53-abnormal (p53abn) EC is associated with abundant copy number alterations and the worst clinical outcome. Patients with p53abn EC have the highest risk of disease recurrence and death, independent of tumor grade and histologic subtype. Currently, all invasive p53abn ECs are considered high risk, and no prognostic biomarkers have yet been found that can aid in clinical management.
View Article and Find Full Text PDFBackground: Knowledge of SARS-CoV-2 household transmission dynamics guides infection control and vaccination measures. This household cohort study prospectively assessed the impact of both the Omicron BA.2 variant and immunity on household transmission using dense saliva sampling and sequence analysis.
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- The study aimed to investigate the prevalence of Pediatric Post-COVID-19 Condition (PPCC), identify associated risk factors, and evaluate the quality of life in children based on the severity of their acute COVID-19 illness.
- A total of 579 children participated, with 260 experiencing mild COVID-19, 60 with severe disease, and 259 as a control group; results indicated that those with severe COVID-19 had a significantly higher prevalence of PPCC compared to mild cases and controls.
- Findings showed that while prevalence of PPCC decreased over time, children exhibiting PPCC had worse physical health-related quality of life and fatigue, with risk factors including prior health issues, hospitalizations, and ongoing fatigue one month post-infection.
Lanthanides are widely assumed not to form covalent bonds due to the localized nature of their 4f valence electrons. This work demonstrates that the ionic bond of Sm(II) with cyclononatetraenyl (η-CH) in [Sm(η-CH)] can be modulated and becomes more covalent by photon-induced transfer of Sm 4f electrons to Sm 5d orbitals. This photon-induced change in bonding properties facilitates a subsequent reconfiguration of [Sm(η-CH)].
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