Publications by authors named "M E Gies"
Article Synopsis
- Plasmacytoid dendritic cells (pDCs) are important for immune responses but are rare in blood and less effective in cancer, making their use in therapies difficult.
- Researchers developed a new method to differentiate pDCs from cord blood stem cells using specific growth factors like SR-1 and GM-CSF, leading to a significant yield of functional pDCs.
- The study found that these cord blood-derived pDCs closely resemble primary pDCs and can potentially enhance anti-tumor immune responses, making them promising candidates for cancer therapies.
Severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) is a serious hazard for hemodialysis (HD) patients and kidney transplant (KTX) recipients as they suffer from an impaired immune response to SARS-CoV-2 vaccination. In addition, a definition of SARS-CoV-2 IgG titer that indicates a sufficient immune response, especially against new omicron variants, is urgently needed. In the present study, the immune response to either a third or a fourth dose of a mRNA vaccine was investigated in 309 dialysis and 36 KTX patients.
View Article and Find Full Text PDFDialysis patients and kidney transplant (KTX) recipients suffer from an impaired immune system and show a decreased response to the severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) vaccination. We performed a retrospective analysis of 1505 serological SARS-CoV-2 measurements obtained from 887 dialysis patients and 86 KTX recipients. The results were separated by patient subgroups (dialysis/KTX) as well as SARS-CoV-2 status.
View Article and Find Full Text PDFThe aim of this work was to study the changes in the functional characteristics of a fermented maize product containing fruits, and enriched with phytosterols. Functional characteristics (natural antioxidants and phytosterols content, in vitro antioxidant capacity and probiotic viability), lipid oxidation, and physicochemical parameters were investigated during 4 weeks of storage at 4 °C. The differences between one formulation elaborated with semi-skimmed powdered milk (Basic Product) and another with whey protein isolate (WPI Product) were evaluated.
View Article and Find Full Text PDFThe capabilities of ion-beam techniques for thin-film processing, i.e., for materials deposition by ion-beam sputtering and surface treatment, are reviewed.
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