[Characteristics of risk factors in young and middle-aged patients with first hemispheric ischemic stroke].

Aim: To compare risk factors of the first hemispheric ischemic stroke in young, middle and old age groups.

Material And Methods: One hundred and thirteen patients with first hemispheric ischemic stroke confirmed by CT/MRI were examined. The patients were divided into 2 groups: young and middle-aged (51 patients, 24 women, 27 men, mean age 49.

[Prognostic aspects of intima-media complex in patients with discirculatory encephalopathy and ischemic heart disease].

Different clinical/instrumental traits and factors of cardiovascular risk in stroke patients of different ages and able-bodied patients with discirculatory encephalopathy are compared. The frequency of some risk factors was even greater in more younger patients compared to older ones while the frequency of enlarged intima-media complex as a parameter of vascular remodeling was similar in both groups. Effects of different risk factors in the aspect of vascular remodeling were evaluated with regression analysis using odds-ratio with 95% confidence interval.

[Phenotypical analysis of children with congenital cleft of upper lip and palate].

The relation between congenital cleft of upper lip and palate with dysplasia of connective tissue was studied. 102 patients (aged from 1 to 14 years) with various kinds of congenital cleft of upper lip and palate were observed. The reports showed phenotypical attributes of dysplasia of connective tissue of patients with similar pathology.

[Comparative assessment of different types of adaptational protection of the myocardium during stress].

Aim: To study in rats effects of 3 types of adaptation on structural rearrangement of myocardium during stress.

Method: Corrosion preparations of coronary vessels, morphometry of focal lesions of cardiomyocytes and correlation analysis of relationships between data obtained by these methods.

Results And Conclusions: Preliminary adaptation to mild stress exerted maximal protection of myocardial cells against severe stress at minimal expansion of coronary vascular bed.

[Cardioprotective effect of combined use of coenzyme Q9 and cyclohexyladenosine in ischemia, reperfusion and acute myocardial infarction].

Effects of coenzyme Q9 (25 mg/kg), N6-cyclohexyl adenosine (CHA, 100 micrograms/kg) and their combination were compared in rats with short-term or permanent ligation of the left coronary artery. The following parameters were evaluated in three series of experiments: 1) incidence and duration of ventricular fibrillation and tachycardia during coronary occlusion (10 min) and consecutive reperfusion (5 min); 2) contractility and electrical stability of the heart (ventricular fibrillation threshold) in animals with 2-day myocardial infarction; 3) ischemic myocardial mass after coronary occlusion (5 min) and necrotic tissue mass in 2-day myocardial infarction. The rats were given oral drugs 5 days and 2 hours before the study.