[Morphological features of oesophagogastric junction mucosa in children with gastroesophageal reflux disease].

In present work we studied the morphological features of the esophageal mucosa in 63 children with gastroesophageal reflux disease (GERD). The biopsies were taken at level of 3 cm above a Z-line and at level of 0.5-1 cm above a Z-line.

[Changes in the fatty acid composition of blood cell membranes in children with inflammatory diseases].

Fatty acid composition of erythrocyte and leukocyte membranes has been studied in children (with normal body mass and obesity) with inflammatory diseases of the gastrointestinal tract and children with bronchial asthma in comparison with basically healthy children. Fifty seven children aged from 7 to 14 years were examined: 13 with inflammatory diseases of the gastrointestinal tract (IDGIT) (eosophagitis, gastroduodenitis, stomach ulcer), 25 with obesity stages (I-III) complicated by IDGIT, 9 with bronchial asthma and 10 basically healthy children. The study revealed that both IDGIT and bronchial asthma caused significant and similar changes in fatty acid composition of cell membranes.

[Morphological changes in esophageal mucosa in children with overweight].

In present work we studied the morphological features of the esophageal mucosa in 63 children with endoscopic diagnosis of the distal esophagitis having overweight and normal weight of a body. The biopsies were taken at level of 3 cm above a Z-line and at level of 1 cm above a Z-line. Dystrophic and dysregenerative changes were revealed at the majority of children and half of children had inflammatory changes of the esophageal mucosa regardless of weight of a body.

[The DNA content in precancer, peripheral cancer and carcinoids of the lung (histospectrophotometric research)].

Histospectrophotometric study of DNA content shows that, at the lung periphery, oval structures with atypia, adenomatosis with atypia, dysplasia and basal cell hyperplasia with bronchial epithelium atypia should be regarded as precancerous lesions. Carcinoma in situ and bronchoalveolar carcinoma are distinguished from the foci of epithelial dysplasia by an increase of DNA content and appearance of hetero- and aneuploidy. Aneuploidy is observed in 97% peripheral lung carcinoma and is combined with a heterogeneity of cells by their DNA content.