Publications by authors named "M E Casperson"
Importance: Adolescent and young adult (AYA) patients with advanced cancer often die in hospital settings. Data characterizing the degree to which this pattern of care is concordant with patient goals are sparse.
Objective: To evaluate the extent of concordance between the preferred and actual location of death among AYA patients with cancer.
Importance: Little is known about the nature of change in goals of care (GOC) over time among adolescents and younger adult (AYA) patients aged 12 to 39 years with cancer near the end of life. Understanding how GOC evolve may guide clinicians in supporting AYA patients in making end-of-life decisions.
Objective: To assess frequency, timing, and evolution of documented GOC among AYA patients with cancer in the last 90 days of life.
: Conceptual models provide frameworks to illustrate relationships among patient-, provider-, system-, and community-level factors that inform care delivery and research. Existing models of cancer survivorship care focus largely on pediatric or adult populations whose needs differ from adolescents and young adults (AYAs). We developed a patient-centered conceptual model of AYA survivorship care.
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- A study investigated how adolescents and young adults with cancer received different types of cancer treatments, such as chemotherapy, targeted therapy, and immunotherapy, in their last 90 days of life between 2009 and 2019.
- Out of 1,836 patients, 35% received chemotherapy, while 24% got targeted therapy, 7% immunotherapy, and 5% investigational drugs, showing a trend toward increased use of these therapies over time.
- Over 50% of the patients received at least one form of systemic cancer-directed therapy in their last three months, highlighting the need to align treatment decisions with the patients' preferences during advanced illness.