Publications by authors named "M E Bodnar"
Article Synopsis
- Claudins, specifically claudin-1 and claudin-4, are tight junction proteins involved in the progression of thyroid cancers and are potential therapeutic targets.
- The study analyzed 162 thyroid samples from patients with various pathologies, finding distinct expression patterns: goiters had negative claudin-1 and mostly positive claudin-4, while papillary thyroid cancers and adenomas showed positive claudin-1 and claudin-4.
- High expression levels of claudin-1 were linked to poorer overall survival rates in patients, highlighting its role as a prognostic factor and indicating a need for further trials to explore claudin targeting in clinical settings.
Isoflurane anesthesia prior to carbon dioxide euthanasia is recognized as a refinement by many guidelines. Facilities lacking access to a vaporizer can use the "drop" method, whereby liquid anesthetic is introduced into an induction chamber. Knowing the least aversive concentration of isoflurane is critical.
View Article and Find Full Text PDFBackground: SARS-CoV-2 can damage human placentas, leading to pregnancy complications, such as preeclampsia and premature birth. This study investigates the histopathological changes found in COVID-19-affected placentas.
Materials And Methods: This study included 23 placentas from patients with active COVID-19 during delivery and 22 samples from patients without COVID-19 infection in their medical history.
Our review aims to clarify the incidence of carotid artery stenosis, risks of development, screening, management, and primary prevention strategies documented in the literature after radiation therapy for head and neck cancers. The high prevalence of carotid stenosis after radiation therapy for head and neck cancers has made surveillance and risk stratification critical. In addition to general cardiovascular risk factors such as smoking, diabetes, and dyslipidemia, risk factors for carotid artery stenosis after head and neck radiation included total plaque score, radiotherapy use and dosage, length of time after radiotherapy, and age greater than 50.
View Article and Find Full Text PDFArticle Synopsis
- * Results showed that there is a wide variation in TM teaching hours across medical schools, with some dedicating less than 2 hours and others more than 4 hours.
- * No significant correlation was found between the number of TM teaching hours and pretest scores among trainees, suggesting a need to improve the content and consistency of TM education in undergraduate programs.