[Methods of making the plaster copies of skulls for the medical and criminalistic identification of individuals].

A possibility was studied to use the plaster copies of skulls in the forensic medical identification of personality by applying the craniofacial method. No dependence was found between the plaster casts and the moulding types. Differences between the same craniometric sizes in the skull and in its cast are of an incidental nature.

[The medical anthropological study of the bone remains from the Yekaterinburg burial].

Results of medical anthropological expert studies of bone remains of Emperor Nicholas II, his family members, and persons in their attendance are presented. Craniological (including computer photoblending), odontological, osteometric, and spectral methods were sued. Numerous photographs, Imperial Family clothes from museums, soil specimens from Tsarskoe Selo and place of burial were used.

[Photoaffinity modification of amino acid derivatives of oligonucleotides in a complementary complex].

Intracomplex photochemical interaction of photoactive derivatives R-CONH(CH2)3NH-pGATACCAA, where R= p-azidotetrafluorophenyl (I) or 2-nitro-5-azidophenyl (II), and 5'-phospho-p-azidoanilide pGATACCAA (III) with a target - oligonucleotide *pGGTATCp (IV) and its derivatives *pGGTATCp-NH(CH2)3NHX, where X = H (V), Phe (VI), or Lys (VII), was studied. According to electrophoretic data, photoreagent (I) gives rise to a covalent photoadduct with compound (IV) as well as with derivatives (VI) and (VII). In the case of reagent (II), only targets (V) - (VII) including aliphatic amino groups participate in the photocoupling.

Photomodification of RNA and DNA fragments by oligonucleotide reagents bearing arylazide groups.

Photomodification of ribo- and deoxyribo-octanucleotides by oligonucleotide reagents (6- and 7-mers) bearing p-azidotetrafluorobenzamido and 2-nitro-5-azidobenzamido groups has been investigated. It is shown that the oligonucleotides with a perfluoroarylazide group were effective modifiers both of deoxyribo- and ribo-targets. Maximum extent of cross-linked product formation (70%) was obtained when the deoxyribo-octanucleotide was modified by a heptanucleotide reagent with a perfluoroarylazide group.