Publications by authors named "M E B Clowse"
Article Synopsis
- The Type 1 and 2 systemic lupus erythematosus (SLE) Model aims to capture all symptoms experienced by SLE patients and is based on prior qualitative research reflecting their lived experiences.
- A qualitative study involving 13 rheumatologists was conducted to gather their feedback on the model's relevance to their clinical practice, with most expressing approval and finding it helpful for treatment and patient education.
- While the model was generally well-received, some rheumatologists raised concerns about its potential to contribute to overdiagnosis of SLE, highlighting the need for further research on its effects on patient interactions and outcomes.
The Impact of Pregnancy Readiness on Lupus Activity, Maternal Mental Health, and Pregnancy Outcomes.
Arthritis Care Res (Hoboken)
September 2024
Article Synopsis
- The study examines how both medical and personal readiness for pregnancy affect various aspects of maternal health in women with systemic lupus erythematosus (SLE).
- Medical readiness is linked to disease activity and pregnancy outcomes, while personal readiness correlates with a patient's perception of their disease and their mental health.
- The findings suggest that improving medical readiness prior to conception can enhance pregnancy outcomes, while addressing unplanned pregnancies may benefit maternal mental health.
Introduction: Medication nonadherence is common in systemic lupus erythematosus (SLE) and associated with morbidity and mortality. We explored the reliability of pharmacy data within the electronic medical record (EMR) to examine factors associated with nonadherence to SLE medications.
Methods: We included patients with SLE who were prescribed ≥1 SLE medication for ≥90 days.
Objectives: Contraception is crucial for safely timing pregnancies in patients with SLE. This study investigated predictors of contraception documentation in patients with SLE, and the alignment of contraception practices with the 2020 American College of Rheumatology (ACR) guidelines, within the Rheumatology Informatics System for Effectiveness (RISE) registry.
Materials And Methods: Female patients (aged 18-44 years) with SLE were identified via International Classification of Diseases (ICD)-9/ICD-10 coding within the RISE registry, which includes data from rheumatology clinics across the USA.
Background And Objective: Upadacitinib is indicated for diseases affecting persons of childbearing potential including rheumatoid arthritis, psoriatic arthritis, axial spondyloarthritis, atopic dermatitis, Crohn's disease, and ulcerative colitis; however, teratogenicity was observed in animal studies. Given the potential for human fetal risk, pregnancy avoidance measures were required during clinical trials. This analysis describes pregnancy outcomes in patients exposed to upadacitinib during pregnancy.
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