Publications by authors named "M Dynis"
Article Synopsis
- Therapeutic plasma exchange (TPE) can effectively remove harmful proteins, but careful management of fluid types and volumes is crucial to avoid low levels of essential proteins, which could lead to complications.
- A study reviewed data from 27 patients undergoing 46 TPE procedures to assess the effectiveness of a predictive mathematical model for estimating post-TPE protein levels.
- Results showed minor adverse events in 25% of patients with no serious complications, indicating that the model can reliably predict protein concentrations and improve patient care during TPE.
Background: Central venous access devices are commonly used in extracorporeal photopheresis, but their performance has not been systematically evaluated. The primary objective of this study was to compare pressures at various flow rates for central venous access devices in an ex vivo simulation of photopheresis.
Study Design And Methods: Diluted, heparinized red blood cells were circulated through central access devices in series with a photopheresis system, and pressures at several flow rates were recorded.
Background: Extracorporeal photopheresis (ECP) is an established treatment for graft-versus-host disease (GVHD). Various haematocrit thresholds have been used to trigger red blood cells transfusion prior to ECP. Moderate-to-severe GVHD is frequently complicated by anaemia; the safety and collection efficiency with a lower haematocrit for ECP is unknown.
View Article and Find Full Text PDFBackground: Extracorporeal photopheresis (ECP) is commonly used to treat patients with graft-versus-host disease (GVHD) and lung transplant rejection (LTR) in our institution. The quantitative relationship between the number of white blood cells treated during ECP and the cell count in peripheral blood is unclear.
Study Design And Methods: Patients with GVHD and LTR receiving ECP with either UVAR XTS or CELLEX (Therakos) were prospectively recruited for this study.
Background: Therapeutic plasma exchange (TPE) is the first-line therapy for patients with thrombotic thrombocytopenic purpura (TTP). However, therapeutic response to TPE and late prognosis vary among different patients, and predictors of these outcomes may help customize treatments to individual patients.
Study Design And Methods: We retrospectively examined the platelet (PLT) recovery rate (PRR) in 64 consecutive patients with initial episode of TTP who received TPE in our institution between 2003 and 2010.