Publications by authors named "M Drancourt"
(), initially isolated from human feces, has been recognised as a distinct taxon within the Archaea domain following comprehensive phenotypic, genetic, and genomic analyses confirming its uniqueness among methanogens. Its diversity, encompassing 15 genotypes, mirrors that of biotic and host-associated ecosystems in which plays a crucial role in detoxifying hydrogen from bacterial fermentations, converting it into mechanically expelled gaseous methane. In microbiota in contact with host epithelial mucosae, centres metabolism-driven microbial networks with , , , , , , , , whereas symbiotic association with the nanoarchaea Nanopusillus phoceensis determines small and large cell variants of .
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- The study focuses on two types of species within a genus that cause Lyme Disease (LD) and Relapsing Fever (RF), highlighting their growing distribution due to climate change and human activities.
- It emphasizes the need for a One Health strategy to understand the interactions between humans, animals, and the environment in the transmission of these diseases.
- A review of existing literature identified 429 relevant studies indicating that several species linked to LD and RF are widespread in vectors, animals, and humans across Mediterranean countries, suggesting a need for monitoring and prevention strategies.
To further assess the spectrum of nanoarchaea in human microbiota, we prospectively searched for nanoarchaea in 110 leftover stool specimens, using the complementary approaches of PCR-sequencing screening, fluorescent hybridization, scanning electron microscopy and metagenomics. These investigations yielded a nanoarchaea, Nanopusillus phoceensis sp. nov.
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