Publications by authors named "M Doi"

In this study, we examined the effect of a bundled approach to blood collection for blood culture on decreasing contamination. Commensal organisms were considered contaminants on the basis of the clinical course if they were recovered from only a single blood draw (set) and if a positive result for two sets was not obtained within 72 hours. The main elements of the bundle were blood collection by venipuncture, skin preparation with a chlorhexidine alcohol swab, disinfection of culture bottles, and use of a sterile blood transfer device instead of the two-needle technique for inoculation.

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Background: Immunoglobulin G4 (IgG4)-related diseases are systemic fibroinflammatory disease characterized by extensive infiltration of IgG4-positive plasma cells in the affected tissue(s), with high plasma levels of IgG4. However, coronary involvement is rare.

Case Summary: A 70-year-old man was diagnosed with IgG4-related coronary arteritis, pancreatitis, and cholangitis during full-body contrast computed tomography (CT) examination prior to surgery for an iliac artery aneurysm.

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Aim: This study aimed to clarify factors that affect turnover intention of nurses in Japanese nursing homes (NHs).

Methods: Cross-sectional nationwide self-administered anonymous questionnaire survey was conducted among 2000 nurses and 1000 directors from 1000 NHs. Data were collected between December 2019 and January 2020.

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Background: Frailty increases the risk of needing nursing care and significantly affects the life and functional prognosis of older individuals. Early detection and tailored interventions are crucial for maintaining and enhancing their life functions. Recognizing distinct clinical phenotypes is essential for devising appropriate interventions.

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Article Synopsis
  • - The study investigates how periodontal disease impacts cognitive function in a mouse model of diet-induced obesity, focusing on the role of microglia, which are immune cells in the brain.
  • - Male C57BL/6 J mice were fed a high-fat diet for 18 weeks to induce obesity and then exposed to a periodontal pathogen to mimic periodontitis over a 6-week period.
  • - Results showed that the obese mice with periodontal infection had cognitive impairments and activated microglia in the brain, and reducing microglia improved their cognitive function, suggesting that microglia play a key role in this link.
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