Alteration of the metabolite interconversion enzyme in sperm and Sertoli cell of non-obstructive azoospermia: a microarray data and in-silico analysis.

Numerous variables that regulate the metabolism of Sertoli cells and sperm have been identified, one of which is sex steroid hormones. These hormones play a vital role in maintaining energy homeostasis, influencing the overall metabolic balance of the human body. The proper functioning of the reproductive system is closely linked to energy status, as the reproductive axis responds to metabolic signals.

Exploring the interaction between immune cells in the prostate cancer microenvironment combining weighted correlation gene network analysis and single-cell sequencing: An integrated bioinformatics analysis.

Background: The rise of treatment resistance and variability across malignant profiles has made precision oncology an imperative in today's medical landscape. Prostate cancer is a prevalent form of cancer in males, characterized by significant diversity in both genomic and clinical characteristics. The tumor microenvironment consists of stroma, tumor cells, and various immune cells.

Climate change: A driver of future conflicts in the Persian Gulf Region?

Ongoing global change and its direct environmental impacts, in addition to securing economic transition to the post-oil era, could trigger complex socio-economic and political crises in oil-dependent economies of the Persian Gulf Region (PGR). To evaluate the role of climate change and related policies in degrading the environment and its socio-economic impacts in the PGR, we have used a variety of available global datasets and published data. The results show that the countries of the PGR pursue some types of socio-economic reforms to alleviate the impacts of climate change.

A Review of C Plants in Southwest Asia: An Ecological, Geographical and Taxonomical Analysis of a Region With High Diversity of C Eudicots.

Southwest Asia is climatically and topographically a highly diverse region in the xeric belt of the Old World. Its diversity of arid habitats and climatic conditions acted as an important area for the evolution and diversification of up to 20 (of 38 known) independent Eudicot C origins. Some of these lineages present unique evolutionary strategies like single-cell functioning C and C-C switching mechanisms.