Total NT-proBNP, a novel biomarker related to recurrent atrial fibrillation.

Background: Novel circulating biomarkers may help in understanding the underlying mechanisms of atrial fibrillation (AF), a challenge for AF management and prevention of cardiovascular (CV) events. Whether glycosylation affects the prognostic value of N-terminal pro-B type natriuretic peptide (NT-proBNP) in AF is still unknown.

Objectives: To test how deglycosylated total NT-proBNP, NT-proBNP and a panel of biomarkers are associated with: (1) recurrent AF, (2) first hospitalization for CV reasons.

Plate-Nematic Phase in Three Dimensions.

We consider a system of anisotropic plates in the three-dimensional continuum, interacting via purely hard core interactions. We assume that the particles have a finite number of allowed orientations. In a suitable range of densities, we prove the existence of a uni-axial nematic phase, characterized by long range orientational order (the minor axes are aligned parallel to each other, while the major axes are not) and no translational order.