Publications by authors named "M Dirnfeld"
Aim: To examine the implantation potential of fragmented embryos that underwent morphokinetic evaluation in a time-lapse incubator.
Methods: A retrospective study analyzing 4210 Day 5 embryos which were incubated in a time-lapse incubator, between 2013 and 2019. Embryos with more than 5% fragmentation (379 embryos) were included in the study.
Article Synopsis
- The study compares the effectiveness of Intra Cytoplasmic Sperm Injection (ICSI) with conventional in vitro fertilization (IVF) using donor sperm in women.
- Results showed no significant differences in fertilization, cleavage, pregnancy, or live birth rates between ICSI and conventional IVF, but ICSI led to a lower proportion of high-quality embryos.
- The findings suggest that ICSI does not improve outcomes related to age-related oocyte quality and may not be the preferred method for insemination in these cases.
Objective: To study whether a powerful, in-house, embryo-selection model can be developed for a specific in vitro fertilization (IVF) laboratory where embryos were already selected for transfer using general models.
Design: In total, 12,944 fertilized oocytes were incubated in an EmbryoScope (Vitrolife, Göteborg, Sweden) at our laboratory. Embryos were selected for transfer or freezing using general models.
In certain patients cleavage stage embryos may be preferred. The relationship between an additional day in culture and pregnancy outcomes is not well established. We aimed to compare outcomes of day 2 versus overnight day 3 frozen embryo transfer (FET).
View Article and Find Full Text PDFBackground: It is still unclear whether endometrial injury (EI) has a beneficial effect on reproductive outcomes, and if so, the optimal procedure characteristics are not clear. All previous papers concluded that more research is needed, and as additional studies were recently published, the insights on EI have changed significantly.
Methods: Searches were conducted in MEDLINE, Embase, Web of Science, and Cochrane Library, to identify randomized controlled trials examining the EI effect on IVF outcomes in women at least one previous failed cycle.