Publications by authors named "M Dioguardi Burgio"

Background: The impact of chronic exercise on cardiometabolic risk is a crucial aspect of public health. However, limited knowledge exists regarding differences in cardiometabolic parameters between older athletes, older controls, and sedentary or active young controls.

Methods: A comprehensive search in major databases until October 2024 was conducted for studies comparing older athletes with older controls or with both sedentary and active younger adults.

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  • A study was conducted on patients who had surgery for high-risk intraductal papillary mucinous neoplasms (IPMNs) that included a mural module, focusing on the relationship between dysplasia grade and the mural module location.
  • The research involved 82 patients, revealing that nearly half had high-grade dysplasia or invasive carcinoma away from the mural module, indicating that local treatment might not be safe or effective.
  • The results suggest that pancreatectomy (removal of part or all of the pancreas) remains the best treatment option due to the potential risks associated with localized treatments.
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  • Disorders of sexual development (DSDs) in dogs, especially prevalent in French Bulldogs, stem from genetic issues and breeding practices affecting genetic diversity.
  • A study on a French Bulldog with ambiguous genitalia utilized advanced genetic techniques and identified a potential connection to a known mutation linked to sex reversal syndrome, along with unusual genetic variants.
  • The results emphasize a higher level of homozygosity in the affected dog, suggesting inbreeding, and call for improved dog genome annotations and responsible breeding practices to manage genetic health.
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Repeat breeder (RB) cows are clinically healthy animals with regular oestrous cycles that do not become pregnant after three or more services. This syndrome has an incidence ranging between 10.1% and 24%.

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  • Heat stress significantly impacts canine reproductive performance and overall health, leading to increased reactive oxygen species (ROS) and sperm dysfunction.
  • A study conducted on 36 male dogs compared those exposed to heat stress (HS) with those in stable temperatures (TN) over 90 days, measuring various health parameters.
  • Results indicated HS dogs experienced decreased protein and antioxidant levels, increased ROS in sperm, and reduced semen quality compared to TN dogs, particularly noticeable after 30 days.
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