Publications by authors named "M Diepold"
The Swiss Blood Stem Cell Transplantation and Cellular Therapy Group (SBST) leads a mandatory national registry for all hematopoietic stem cell transplants (HCT) and cellular therapies. After 25 years, information was available for 11,226 patients receiving an HCT (4031 allogeneic and 7195 autologous), including 925 pediatric patients. We compared patient characteristics and outcome by quinquennia 1997-2001, 2002-2006, 2007-2011, 2012-2016, and 2017-2021.
View Article and Find Full Text PDFDiamond-Blackfan anemia (DBA) is a congenital bone marrow failure syndrome associated with malformations. DBA is related to defective ribosome biogenesis, which impairs erythropoiesis, causing hyporegenerative macrocytic anemia. The disease has an autosomal dominant inheritance and is commonly diagnosed in the first year of life, requiring continuous treatment.
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- Most patients with hemoglobinopathies have a strong desire for parenthood, with 75.9% expressing this wish, regardless of demographic factors.
- Fertility counseling and testing are often overlooked, as only 28.8% of patients recalled receiving counseling and 11.6% remembered undergoing fertility testing.
- There is a significant gap in fertility preservation utilization, with only 5.4% of patients taking advantage of available options, highlighting the need for improved patient education and counseling on fertility risks.