Publications by authors named "M Diaz-Curiel"
Article Synopsis
- * The authors advocate for keeping ethnic and race-specific FRAX models in the US, suggesting they should be based on updated data related to fracture and death risks.
- * The position opposing fixed bone mineral density thresholds is supported by the International Osteoporosis Foundation (IOF) and the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO), emphasizing the need for equity in fracture risk assessment.
Vitamin D is important for musculoskeletal health. Concentrations of 25-hydroxyvitamin D, the most commonly measured metabolite, vary markedly around the world and are influenced by many factors including sun exposure, skin pigmentation, covering, season and supplement use. Whilst overt vitamin D deficiency with biochemical consequences presents an increased risk of severe sequelae such as rickets, osteomalacia or cardiomyopathy and usually warrants prompt replacement treatment, the role of vitamin D supplementation in the population presents a different set of considerations.
View Article and Find Full Text PDFObjective: This study aimed to evaluate the bone microstructure to determine whether curative surgery of primary hyperparathyroidism produces changes in bone mineral density (BMD), trabecular bone score (TBS), and three-dimensional (3D) dual x-ray absorptiometry (DXA) parameters and whether these changes are comparable.
Methods: We retrospectively studied 85 patients (60 women and 25 men, 60.4 ± 12.
Article Synopsis
- The study aimed to assess how various non-osteoporotic medications affect the risk of fragility fractures in patients already on anti-osteoporotic therapy.
- Researchers analyzed data from 993 patients to compare the effects of different medications, noting thiazides and statins as potentially beneficial, while observing certain drugs like letrozole and oral corticosteroids as harmful.
- Results showed no significant improvement in fracture risk from treatments, but identified that letrozole and low-to-medium dose oral corticosteroids significantly worsened fracture risk, highlighting the need for stronger anti-osteoporotic options for those patients.
Introduction: EQ-5D-3L preference-based value sets are predominately based on hypothetical health states and derived in cross-sectional settings. Therefore, we derived an experience-based value set from a prospective observational study.
Methods: The International Costs and Utilities Related to Osteoporotic fractures Study (ICUROS) was a multinational study on fragility fractures, prospectively collecting EQ-5D-3L and Time trade-off (TTO) within two weeks after fracture (including pre-fracture recall), and at 4, 12, and 18 months thereafter.