Publications by authors named "M Diaz de Leon Ponce"
The human deoxyribonucleoside triphosphatase (dNTPase) Sterile alpha motif and histidine-aspartate domain containing protein 1 (SAMHD1) has a dNTPase-independent role in repairing DNA double-strand breaks (DSBs) by homologous recombination (HR). Here, we show that VENOSA4 (VEN4), the probable ortholog of SAMHD1, also functions in DSB repair by HR. The loss-of-function mutants showed increased DNA ploidy and deregulated DNA repair genes, suggesting DNA damage accumulation.
View Article and Find Full Text PDFBackground And Aims: The COVID-19 pandemic significantly impacted the mental health of healthcare professionals, especially those working in Psychosocial Care Centers (CAPS), which are crucial services in the Brazilian mental health system. This study aimed to investigate the association between job satisfaction, workload, and psychological distress among CAPS professionals during the pandemic.
Methods: A cross-sectional study was conducted with 53 professionals from seven CAPS.
Zinc knuckle (ZCCHC) motif-containing proteins are present in unicellular and multicellular eukaryotes, and most ZCCHC proteins with known functions participate in the metabolism of various classes of RNA, such as mRNAs, ribosomal RNAs, and microRNAs. The Arabidopsis (Arabidopsis thaliana) genome encodes 69 ZCCHC-containing proteins; however, the functions of most remain unclear. One of these proteins, CAX-INTERACTING PROTEIN 4 (CXIP4, encoded by AT2G28910), has been classified as a PTHR31437 family member.
View Article and Find Full Text PDFArticle Synopsis
- CeO samples were made using the polymeric precursor method with varying calcination temperatures, leading to changes in particle size and shape.
- Advanced techniques like positron annihilation lifetime spectroscopy (PALS) and electron paramagnetic resonance (EPR) revealed the presence of different types of oxygen vacancies associated with various cerium ions.
- Impedance spectroscopy showed that as the calcination temperature increased, there was a reduction in electrical conductance and the formation of polarons in the material.
Article Synopsis
- - This study examined how replacing soybean meal and corn with field peas in the diets of dairy cows affects their milk production, feed intake, and blood indicators.
- - Twelve Holstein-Friesian cows participated in a controlled diet study, with three different treatments involving varying amounts of field peas in their concentrate feed.
- - Results showed that milk production and overall feed intake were not significantly affected by replacing soybean meal and corn with field peas, suggesting peas are a viable alternative without compromising milk quality.