Publications by authors named "M Dia"
Recent Molecular Epidemiology of Echovirus 11 Throughout North and West Africa Resulted in the First Identification of a Recombinant Strain from an Acute Flaccid Paralysis Case in West Africa.
Viruses
November 2024
Article Synopsis
- Echovirus 11 is causing increasing cases of neonatal sepsis in Europe and limited reports in West Africa, highlighting a significant public health issue.
- A study analyzed 23 E11 strains from West Africa using high-throughput sequencing, marking the first molecular characterization of the virus in the region and revealing a new recombinant strain.
- The research indicates that E11 has evolved into four distinct clades since the 1970s, with instances of the virus spreading from West Africa to Europe, underscoring the need for enhanced surveillance of enteroviruses in Africa.
Wesselsbron is a neglected, mosquito-borne zoonotic disease transmitted by several species of virus-infected Aedes mosquitoes endemic to tropical regions in Africa. It affects primarily domestic livestock species with teratogenic effects, but can jump to humans. Herein, we investigated the molecular epidemiology of Wesselsbron virus in Africa using whole genome sequencing and structural analysis, and assessed its pathogenicity and tropism through in vivo experiments.
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- The study investigates how humic acid (HA) interacts with engineered nanoparticles (NPs) in natural waters using H 2D METR NMR spectroscopy.
- Significant changes in T relaxation times of HA were observed when varying concentrations of carboxyl-functionalized iron oxide nanoparticles (NPCOs) were added, particularly affecting lipids and carbohydrates.
- The findings suggest that smaller molecules within these regions are the first to interact with NPCOs, impacting the HA system overall, which is crucial for understanding the environmental behavior of nanoparticles.
Background: The heart expresses 2 main subtypes of cAMP-dependent protein kinase (PKA; type I and II) that differ in their regulatory subunits, RIα and RIIα. Embryonic lethality of RIα knockout mice limits the current understanding of type I PKA function in the myocardium. The objective of this study was to test the role of RIα in adult heart contractility and pathological remodeling.
View Article and Find Full Text PDFPaying attention to uncertainty: A stochastic multimodal transformers for post-traumatic stress disorder detection using video.
Comput Methods Programs Biomed
December 2024
Background And Objectives: Post-traumatic stress disorder is a debilitating psychological condition that can manifest following exposure to traumatic events. It affects individuals from diverse backgrounds and is associated with various symptoms, including intrusive thoughts, nightmares, hyperarousal, and avoidance behaviors.
Methods: To address this challenge this study proposes a decision support system powered by a novel multimodal deep learning approach, based on a stochastic Transformer and video data.