STAT3-related lncRNAs in colorectal cancer progression; Special focus on immune cell's evasion.

Colorectal cancer (CRC) is globally ranked as the third leading cause of cancer-related deaths in both men and women. There is an urgent need for novel biomarkers to facilitate early diagnosis and enhance patient care, thereby improving treatment response and reducing mortality rates. Signal transducer and activator of transcription 3 (STAT3) is essential for controlling the anti-tumor immune response since it is a hub for several oncogenic signaling pathways.

A Comparative Study of the Efficacy of Platelet-Rich Plasma (PRP) vs. Other Conservative Treatments for Lateral Epicondylitis.

Background Lateral epicondylitis, also known as tennis elbow, is a degenerative condition that affects a significant portion of the adult population, particularly those between the ages of 35 and 55. Conventional treatments, including analgesics, physiotherapy, and bracing, often lead to a high recurrence rate. Platelet-rich plasma (PRP) therapy has emerged as a promising alternative, offering regenerative benefits that may enhance tissue healing.

A Study Examining the Functional Outcomes of Conservative and Surgical Management of Three- and Four-Part Proximal Humerus Fractures in Individuals Aged Over 50 Years.

Background:  Proximal humerus fractures are common in elderly patients and are often associated with osteoporosis. The management of these fractures, particularly three-part and four-part fractures, remains controversial, with conservative and surgical treatments both employed. This study compared conservative and surgical management's functional outcomes in subjects over 50 years.

Adult Laryngotracheobronchitis in the Setting of a COVID-19 Infection.

We describe a case of adult croup in an 18-year-old female caused by the SARS-CoV-2 virus. Her complaints started as lower respiratory tract symptoms that evolved into stridor, barking cough, and dyspnea. The patient was diagnosed with SARS-CoV-2 by reverse transcription-polymerase chain reaction (RT-PCR) testing from a nasopharyngeal swab.