Publications by authors named "M Desnos-Ollivier"

Article Synopsis
  • Malassezia spp. are naturally found in various parts of the human body, including the skin and gut, but are challenging to culture, leading to the development of molecular methods like pan-M-qPCR for detection.
  • The study tested this method on 361 clinical samples from different patient groups to assess Malassezia levels, revealing higher quantities in seborrheic dermatitis and burned patients compared to healthy individuals.
  • Results showed that the pan-M-qPCR is effective for quantifying Malassezia, highlighting its higher presence in specific areas of the body and its potential as a valuable tool for studying this fungal genus in human microbiomes.
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Article Synopsis
  • - A new species of yeast called Trichosporon austroamericanum sp. nov. was identified during an epidemiological survey of a kidney transplant recipient from Brazil, based on a urine sample.
  • - The strain was characterized using molecular techniques, specifically the intergenic spacer (IGS1) ribosomal DNA locus, revealing its close relation to Trichosporon inkin but highlighting its uniqueness.
  • - T. austroamericanum can be differentiated from other related Trichosporon species through distinct morphological, physiological, and phylogenetic traits.
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Objectives: We aimed to describe features and outcomes of cryptococcosis among HIV-seronegative individuals in a large surveillance network for cryptococcosis in France.

Methods: We included incident cases of cryptococcosis in HIV-seronegative individuals from 2005 to 2020. We compared patient characteristics, disease presentations, cryptococcal antigen results, and induction antifungal treatments according to underlying disease.

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Among 1107 cryptococcosis cases from the French surveillance network (2005-2020), the proportion of HIV-seronegative individuals has recently surpassed that of HIV-seropositive individuals. We observed marked differences in patient characteristics, disease presentations, cryptococcal antigen results, infecting species, and mortality according to HIV serostatus.

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Hybrid AD strains of the human pathogenic Cryptococcus neoformans species complex have been reported from many parts of the world. However, their origin, diversity, and evolution are incompletely understood. In this study, we analyzed 102 AD hybrid strains representing 21 countries on five continents.

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