Publications by authors named "M Deraco"
To provide evidence-based guidelines about Peritoneal Surface Malignancy (PSM) treatment for the Peritoneal Surfaces Oncology Group International. The GRADE ADOLOPMENT method was used to adapt recommendations from the Italian Medical Oncology Association Guideline on PSM. Seven scientific society were involved to form five guideline panels composed of 28 medical professionals from 14 countries.
View Article and Find Full Text PDFColorectal peritoneal metastases (CPM) are common in colorectal cancer patients. This article aims to provide GRADE guidelines for the use of hyperthermic intraperitoneal chemotherapy (HIPEC) in two clinical situations: (1) To determine the value of adjuvant HIPEC for the prevention of CPM in high-risk colorectal cancer patients; (2) to determine the impact on survival of cytoreductive surgery and HIPEC followed by adjuvant systemic chemotherapy as compared to systemic chemotherapy alone in patients with CPM.
View Article and Find Full Text PDFBackground And Objectives: Few preclinical models of pseudomyxoma peritonei (PMP) have been developed, probably due to the tumor's low incidence and its peculiar characteristics of slow growth. Therefore, there is a need to develop more refined PMP models that better reflect its characteristics. The aim of the study is to develop a culture strategy to generate organoid models derived from PMP patient samples.
View Article and Find Full Text PDFArticle Synopsis
- Peritoneal surface oncology (PSO) focuses on understanding and managing cancerous growths in the peritoneal cavity, which can be either primary or secondary.
- There is an increasing demand for specialized training for surgical oncologists in this area to address the gap in expertise and improve patient outcomes.
- The European School of Peritoneal Surface Oncology (ESPSO) was established in 2014 to offer education and training in this emerging field.
Article Synopsis
- The PRECINCT study evaluated how different morphological appearances of peritoneal malignancies on imaging related to pathological findings in a large patient group.
- It involved the analysis of imaging from 630 patients across seven centers, using 24 morphological terms to describe peritoneal tumors, highlighting high pathological positivity rates for several specific appearances.
- The study recommends standardizing morphological descriptions in radiology reports to improve diagnostic accuracy and proposes that expert radiologists develop a consensus on terminology for better communication in clinical practice.