Publications by authors named "M Demmler"

Synthetic dyes are found in a wide variety of applications today, including but not limited to textiles, foods, and medicine. The analysis of these molecules is pertinent to several fields such as forensics, environmental monitoring, and quality control, all of which require the sensitivity and selectivity of analysis provided by mass spectrometry (MS). Recently, there has been an increase in the implementation of MS evaluation of synthetic dyes by various methods, with the majority of research thus far falling under electrospray ionization and moving toward direct ionization methods.

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Dyes have become common substances since they are employed in mostly all objects surrounding our daily activities such as clothing and upholstery. Based on the usage and disposal of these objects, the transfer of the dyes to other media such as soil and water increases their prevalence in our environment. However, this prevalence could help to solve crimes and pollution problems if detection techniques are proper.

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Article Synopsis
  • HIV-1 infection causes dysfunction in myeloid dendritic cells (DCs), reducing their effectiveness in responding to vaccines.
  • The study explored the use of recombinant Listeria monocytogenes (Lm) vectors to activate DCs from HIV-infected donors, showing they can stimulate immune responses despite the suppressive effects of HIV plasma.
  • Findings indicated that Lm vectors not only enhance immune activation but also reactivate latent HIV proviruses, suggesting a potential strategy for therapeutic vaccination and reducing latent infection pools.
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Background: It has been hypothesized in the literature that exposure to extremely low frequency electromagnetic fields (50 or 60 Hz) may lead to human health effects such as childhood leukemia or brain tumors. In a previous study investigating multiple types of cells from brain and kidney of the mouse (Acta Neuropathologica 2004; 107: 257-264), we found increased unrepaired nuclear DNA single strand breaks (nDNA SSB) only in epithelial cells of the choroid plexus in the brain using autoradiographic methods after a continuous eight-week 50 Hz magnetic field (MF) exposure of adult mice with flux density of 1.5 mT.

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Background: We investigated incremental cost of nosocomial pneumonia (NP) from the perspective of a hospital and health insurance funds.

Patients And Methods: The incremental cost was determined by calculating total costs for pneumonia patients and controls using prospective and retrospective matched-pairs analysis with 29 and 37 matched pairs, respectively.

Results: Compared to controls, patients who developed pneumonia had to be on artificial ventilation 5 days longer, needed markedly more intensive care with 6.

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