Distinct amino acid substitutions in the EEV glycoprotein and DNA-dependent RNA polymerase of lumpy skin disease virus identified in wetland areas of Bangladesh.

The recent outbreak of lumpy skin disease virus (LSDV) in the wetland areas of Bangladesh presents a significant concern for both animal health and regional biosecurity. Epidemiological investigations into nine major outbreaks in the wetland areas revealed distinctive clinical symptoms in affected cattle, including elevated body temperature, excessive salivation, and the presence of skin nodules. Histopathological examination unveiled larger nodules compared to previous outbreaks, along with signs of secondary infection.

AqUavplant Dataset: A High-Resolution Aquatic Plant Classification and Segmentation Image Dataset Using UAV.

Aquatic vegetation species are declining gradually, posing a threat to the stability of aquatic ecosystems. The decline can be controlled with proper monitoring and mapping of the species for effective conservation and management. The Unmanned Ariel Vehicle (UAV) aka Drone can be deployed to comprehensively capture large area of water bodies for effective mapping and monitoring.

DNA damage causes ATM-dependent heterochromatin loss leading to nuclear softening, blebbing, and rupture.

The nucleus must maintain stiffness to preserve its shape and integrity to ensure proper function. Defects in nuclear stiffness caused from chromatin and lamin perturbations produce abnormal nuclear shapes common in aging, heart disease, and cancer. Loss of nuclear shape via protrusions called blebs lead to nuclear rupture that is well-established to cause nuclear dysfunction, including DNA damage.

Unmasking heavy metal contamination: Tracing, risk estimating and source fingerprinting from coastal sediments of the Payra River in Bangladesh.

The Payra River, cicual for fish breeding, feeding and nursery in coastal Bangladesh, faces heavy contamination from industrial activities, agricultural runoff and poor waste management. This study used ICP-MS to assess metal contamination levels, risk status and potential sources in river sediment. The findings showed that the mean concentrations (mg/kg) of metals followed the decreasing order: Mn (434.

Network Pharmacology and In Silico Elucidation of Phytochemicals Extracted from Ajwa Dates (Phoenix dactylifera L.) to Inhibit Akt and PI3K Causing Triple Negative Breast Cancer (TNBC).

Background: About 10-15% of all breast cancers comprise triple-negative breast cancer (TNBC), defined as cancer cells that lack receptors for the ER, PR, and HER2 protein receptors. Due to the absence of these receptors, treating TNBC using conventional chemotherapy is challenging and, therefore, requires the discovery of novel chemotherapeutic agents derived from natural sources.

Objective: The current work was intended to study the potential phytochemicals of Ajwa dates (Phoenix dactylifera L.