Publications by authors named "M Delaplace"
Article Synopsis
- - Infection with simian foamy viruses (SFVs) can result in lifelong infections in humans but typically do not cause severe disease or human-to-human transmission, making them an interesting case study for zoonotic retroviruses.
- - Researchers studied neutralizing antibodies (nAbs) in SFV-infected individuals from Central Africa, focusing on the viral envelope protein's variable regions, which are crucial for nAb targeting and do not exhibit major immune escape mechanisms.
- - Three primary regions crucial for nAb binding were identified, and they play a role in preventing the virus from changing shape or binding to human cells, effectively blocking infection.
Article Synopsis
- The report details the case of a 5-year-old obese male cat (Cat-1) that presented with severe heart failure and was found to have SARS-CoV-2-associated myocarditis after being in close contact with an owner who tested positive for COVID-19.
- Cat-1 showed high levels of cardiac troponin-I, suggesting heart damage, and had both clinical and echocardiographic signs of heart disease, while another cat in the same household (Cat-2) remained asymptomatic despite also testing positive for SARS-CoV-2.
- After treatment with cardiac medications and antibiotics, Cat-1 made a full recovery within a month, exhibiting improvements in heart function and the absence of heart failure and pulmonary issues
Feline coronaviruses (FCoV) are common viral pathogens of cats. They usually induce asymptomatic infections but some FCoV strains, named Feline Infectious Peritonitis Viruses (FIPV) lead to a systematic fatal disease, the feline infectious peritonitis (FIP). While no treatments are approved as of yet, numerous studies have been explored with the hope to develop therapeutic compounds.
View Article and Find Full Text PDFAfter its first description in Wuhan (China), SARS-CoV-2 the agent of coronavirus disease 2019 (COVID-19) rapidly spread worldwide. Previous studies suggested that pets could be susceptible to SARS-CoV-2. Here, we investigated the putative infection by SARS-CoV-2 in 22 cats and 11 dogs from owners previously infected or suspected of being infected by SARS-CoV-2.
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