Publications by authors named "M Delannoy"

Article Synopsis
  • Organochlorine pesticides (OCPs) differ in chemical structure and toxicity mechanisms but share common traits like persistence and bioaccumulation, contributing to health problems.
  • Despite extensive knowledge on OCP toxicity, the specific molecular mechanisms impacting mammals remain partially unknown, prompting this review to explore their modes of action.
  • The review focuses on three widely used OCPs—Dichlorodiphenyltrichloroethane, Hexachlorocyclohexane, and Chlordecone—examining their biological responses and interactions in human and animal bodies.
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The use of Sargassum spp., a brown invasive algae, for the production of biochars (BCs) or activated carbons (ACs) and their efficiency to sequestrate chlordecone (CLD) in soil has been recently suggested. The objective of this study was to assess the potential of microwave prepared Sargasso biochar (BCS) amendment in Andosol on the bioavailability of chlordecone in laying hens and piglets, when exposed to this matrix.

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Proteasomes are critical for peripheral nervous system (PNS) function. Here, we investigate mammalian PNS proteasomes and reveal the presence of the neuronal membrane proteasome (NMP). We show that specific inhibition of the NMP on distal nerve fibers innervating the mouse hind paw leads to reduction in mechanical and pain sensitivity.

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Government monitoring commonly includes regulating POPs in animal feed and products of animal origin, with many countries setting Maximum Residue Levels (MRLs) to ensure safe tolerable concentrations. However, these MRLs do not address the presence of most POP families in soil, where concentrations can be much higher due to the contaminants' strong affinity and persistence in comparison to other environmental matrices. Extensive damage to food and production systems during a pollution incident causing soil contamination by POPs lead to severe economic and social consequences for the affected area.

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