Publications by authors named "M Del Rocio Martinez-Alvarado"
Low HDL-C/ApoA-I index is associated with cardiometabolic risk factors and coronary artery calcium: a sub-analysis of the genetics of atherosclerotic disease (GEA) study.
BMC Endocr Disord
July 2024
Article Synopsis
- The study investigates the HDL-C/ApoA-I index as a potential marker for atherosclerosis and its relationship with cardiometabolic risk factors in a sample of 1,363 individuals aged 20-75, none of whom had coronary heart disease or diabetes.
- Results show that lower HDL-C/ApoA-I index values are linked to higher prevalence of adverse conditions like metabolic syndrome, fatty liver, and coronary artery calcification (CAC).
- The findings suggest that the HDL-C/ApoA-I index could serve as a practical biomarker for assessing cardiometabolic risks and subclinical atherosclerosis in adults.
Impact of Lipids and Vascular Damage on Early Atherosclerosis in Adolescents with Parental Premature Coronary Artery Disease.
High Blood Press Cardiovasc Prev
January 2024
Aim: To assess the relationship of cardiovascular risk factors (CRFs) with carotid intima media thickness (IMT) in adolescents with a parental history of premature coronary artery disease (PCAD).
Methods: This cross-sectional study included 50 healthy adolescents, aged 14-18 years, both sexes, with a parental history of PCAD, that were compared to 50 controls without this history. Questionnaires regarding information of CRFs were applied.
Increased carotid intima-media thickness and cardiometabolic risk factors are associated with IL-6 gene polymorphisms in Mexican individuals: The Genetics of Atherosclerotic Disease Mexican study.
Biomol Biomed
March 2024
Interleukin 6 (IL-6) is a cytokine implicated in the development of atherosclerosis. This study aimed to determine the association of three IL-6 gene polymorphisms with increased carotid intima-media thickness (CIMT) and cardiometabolic risk factors. Three IL-6 polymorphisms (rs1800795, rs2069827, and rs1800796) were analyzed in 178 individuals with increased CIMT (CIMT ≥ 75th percentile) and 906 individuals without increased CIMT (CIMT < 75th percentile).
View Article and Find Full Text PDFExaggerated blood pressure elevation in response to orthostatic challenge, a post-acute sequelae of SARS-CoV-2 infection (PASC) after hospitalization.
Auton Neurosci
July 2023
Objective: Post-acute sequelae of SARS-COV-2 (PASC) are emerging as a major health challenge. Orthostatic intolerance secondary to autonomic failure has been found in PASC patients. This study investigated the effect of COVID-19 after recovery on blood pressure (BP) during the orthostatic challenge.
View Article and Find Full Text PDFEffect of metabolic control on recurrent major adverse cardiovascular events and cardiovascular mortality in patients with premature coronary artery disease: Results of the Genetics of Atherosclerotic Disease study.
Nutr Metab Cardiovasc Dis
September 2022
Background And Aims: Coronary artery disease (CAD) is the leading cause of death around the world, and its rate of presentation is increasing at young ages. Despite the evidence that secondary prevention in CAD reduces the risk of recurrent major adverse cardiovascular events (MACE), no studies have analyzed the composite control of blood pressure, lipids, and glucose control in premature CAD.
Methods And Results: This was a real-world prospective cohort study of patients with premature CAD.