Advanced mass spectrometry profiling of phenolic and minerals compounds in herbal beverages.

The global pandemic of COVID-19 has led to an increased interest in herbal infusions as natural remedies since 2020. This has also heightened the need for controlling the composition of these dietary supplements to ensure consumer health and prevent food fraud. In the present work, various mass spectrometry techniques were used to analyze the organic and inorganic composition of 23 herbal infusion samples.

Improved physical and osteoinductive properties of demineralized bone matrix by gelatin methacryloyl formulation.

The demineralized bone matrix (DBM) is the most widely used bone allograft, which is obtained by removing the mineral component of bone, leading to exposure of the proteins responsible for osteoinduction. For clinical use, DBM shall be formulated with a carrier that provides consistency and improves its osteoinduction. In this study, three DBM formulations with glycerol (Gly), hyaluronic acid (HA), and gelatin methacryloyl (GelMA) were evaluated measuring their physicochemical properties (microstructure, compressive strength, and serum cohesivity) and their osteoinductive capacity both in vitro using C2C12 cells and umbilical cord human mesenchymal stem cells and in vivo in an ectopic bone formation model in athymic mice.

The different satiating capacity of CHO and fats can be mediated by different effects on leptin and ghrelin systems.

Leptin and ghrelin are known to be the main hormones involved in the control of food intake, with opposite effects. Here we aimed to assess whether changes in leptin and ghrelin systems can be involved in the different satiating capacities of carbohydrates (CHO) and fat. Adult male Wistar rats were studied under 24h fasting conditions and after 24h fasting followed by a 12h re-feeding period with 64 kcal of CHO or fat, consisting of a mixture of wheat starch and sucrose or bacon, respectively.