Publications by authors named "M Del Cuerpo"
Introduction: Enteroviruses are a type of RNA-strained virus with more than 100 different genotypes. Infection can be asymptomatic, and, if any, symptoms can range from mild to severe. Some patients can develop neurological involvement, such as aseptic meningitis, encephalitis, or even cardiorespiratory failure.
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- The study compares viral culture and qPCR for detecting human cytomegalovirus (HCMV) in bronchoalveolar lavage (BAL) fluid, aiming to find a viral load threshold for identifying HCMV-related pneumonitis.
- Out of 176 BAL samples, 81.25% showed concordant results; however, qPCR identified HCMV in some samples that culture did not, highlighting challenges in result interpretation.
- A threshold of 1258 IU/mL in BAL fluid was determined, showing strong sensitivity and specificity for diagnosing pneumonia, indicating that qPCR can efficiently rule out HCMV pneumonitis when negative, though positive results may not always signal significant lung replication.
Article Synopsis
- Influenza B viruses have segmented genomes which allow them to evolve through reassortment, with two lineages, B/Victoria and B/Yamagata, having distinct evolutionary histories since their divergence.
- This study analyzed FLUBV strains from patients at two hospitals in Barcelona between 2004 and 2015, utilizing various detection methods and whole genome sequencing for characterization.
- Results found 118 FLUBV strains, revealing significant intra-lineage reassortments and identifying various clades, emphasizing the ongoing evolution and genetic diversity of these viruses.
Background: Knowing how long SARS-CoV-2-positive individuals can remain infective is crucial for the design of infection prevention and control strategies. Viral culture is the gold standard for detecting an active-replicative virus and evaluating its infectious potential.
Objective: To assess the correlation of SARS-CoV-2 infectivity with the number of days from symptom onset and the Ct value, using culture as a reference method.
Article Synopsis
- Echovirus 30 (E30) is an enterovirus linked to neurological diseases, with significant interest due to its role in hospitalizations, yet long-term epidemiological studies are limited.* -
- This research analyzed E30 infections over 26 years by evaluating data from a lab database, where it was found in 173 out of 2402 detected enterovirus infections, primarily linked to neurological issues in patients.* -
- The study identified two main E30 lineages circulating in Catalonia from 1996 to 2016 (E and F), with lineage F being predominant, and noted that a new lineage (I) became dominant in 2018.*