Urinary PCA3 to predict prostate cancer in a cohort of 1015 patients.

Aim: To evaluate the performance of urinary PCA3 test to predict prostate biopsy outcome in a large French cohort.

Patients And Methods: A urine sample was prospectively obtained in 1015 patients undergoing prostate biopsies to determine the PCA3 score. The predictive value of PCA3 was explored using receiver operating characteristic curve analysis (ROC), multivariable logistic regression analysis and decision curve analysis.