Publications by authors named "M De La Calle"
Introduction: Traditional multivariate methods for neuroimaging studies overlook the interdependent relationship between brain features. This study addresses this gap by analyzing relative brain volumetric patterns to capture how Alzheimer's disease (AD) and genetics influence brain structure along the disease continuum.
Methods: This study analyzed data from participants across the AD continuum from the Alzheimer's and Families (ALFA) and Alzheimer's Disease Neuroimaging Initiative (ADNI) studies.
Macromolecular interaction mechanism of the bacteriocin EntDD14 with the receptor binding domain (RBD) for the inhibition of SARS-CoV-2 and the JN.1 variant: Biomedical study based on elastic networks, stochastic Markov models, and macromolecular volumetric analysis.
Biophys Chem
December 2024
Bacteriocins, a class of molecules produced by bacteria, exhibit potent antimicrobial properties, including antiviral activities. The urgent need for treatments against SARS-CoV-2 has proposed bacteriocins such as enterocin DD14 (EntDD14) as potential therapeutic agents. However, the mechanism of macromolecular interaction of EntDD14 for the inhibition of SARS-CoV-2 is not yet fully understood, and its efficacy against variants like JN.
View Article and Find Full Text PDFObjectives: Triplet pregnancies are high-risk pregnancies, and its baseline characteristics and gestational care protocols have changed over the years. The objective of this study is to compare the baseline characteristics and the prevalence of maternal, fetal, obstetric, and perinatal outcomes between triplet pregnancies conceived between 2013 and 2024 (period II [PII]) and those conceived between 2000 and 2012 (period I [PI]).
Methods: This was a single-centre, observational retrospective case-control study that included all triplet pregnancies followed up at the La Paz University Hospital between 2000 and 2024.
Article Synopsis
- - The study focuses on developing two new questionnaires, MatCODE and MatER, to assess women's knowledge of healthcare rights and their perception of resource scarcity during pregnancy, labor, and the early postpartum period.
- - Experts validated the content of these tools using the Aiken's V coefficient and content validity index, and a pilot cohort established face validity through the INFLESZ scale.
- - The results showed that both questionnaires have strong psychometric properties, including good reliability (ω and α values) and appropriate validation measures, indicating their effectiveness for monitoring maternal healthcare in Spain.
School nutrition is an important key modifier in terms of child and adolescent nutrient intake [...
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