Publications by authors named "M De Ceano-Vivas"
Impact of nirsevimab immunization on RSV infections attended in the pediatric emergency department: First results in a tertiary hospital in Madrid.
Miguel Ángel Molina Gutiérrez Begoña de Miguel Lavisier José Antonio Ruiz Domínguez María García de Oteyza Virginia María Velasco Molina María de Ceano-Vivas
Enferm Infecc Microbiol Clin (Engl Ed)
August 2024
Article Synopsis
- Human respiratory syncytial virus (RSV) is a leading cause of respiratory infections, and the immunization campaign with the monoclonal antibody nirsevimab started in October 2023.
- A study at a Pediatric Emergency Department in Madrid analyzed RSV infection cases among children eligible for nirsevimab immunization during specific weeks in 2022 and 2023.
- Results showed a significant drop in emergency visits for RSV in 2023 compared to 2022, indicating that nirsevimab effectively reduced RSV-related consultations during the epidemic season.
Article Synopsis
- Enterovirus D68 (EV-D68) infections can cause severe respiratory issues and acute flaccid myelitis, with a significant rise reported during the fall-winter season of 2021-2022 across Europe.
- The study by the European Non-Polio Enterovirus Network (ENPEN) analyzed over 10,481 samples from 19 countries, identifying 1,004 as EV-D68, predominantly affecting young children, where 37.9% required hospitalization.
- Additionally, genetic analyses uncovered two new B3-derived lineages without regional patterns, indicating a notable impact of the infections and the emergence of new virus strains.
Objectives: Rapid management of patients with respiratory tract infections in hospital emergency departments is one of the main objectives since the concurrent circulation of respiratory viruses following the SARS-CoV-2 pandemic. The use of new combined point-of-care antigen tests for detecting influenza A/B and SARS-CoV-2 represents an advantage in response time over the molecular tests. The objective was to evaluate the suitability of the CLINITEST® Rapid Covid-19 + Influenza Antigen test (Siemens Healthineers, Germany) (RCIA test) by measuring the sensitivity, specificity, Cohen's kappa, and cut-off values.
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