Publications by authors named "M Dasgupta"

Absence of the ductus arteriosus (DA) is common in tetralogy of Fallot (TOF), occurring in up to 30% of cases. Yet, the clinical course and fetal echocardiographic features are not well described, limiting prenatal counseling. This study examines the fetal echocardiographic characteristics and perinatal outcomes in children with TOF absent DA (TOF/ADA), comparing them to those with a DA (TOF/DA).

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, an opportunistic pathogen often causes biofilm-linked infections. A combinatorial approach involving tetracycline (antibiotic) and cuminaldehyde (phytochemical) was explored to combat this infectious pathogen. The results showed that both tetracycline and cuminaldehyde individually demonstrated antibacterial effects.

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Apples are preserved in cold storage within standard size crates to avoid injury during handling and are stacked in a specific manner to promote adequate air circulation. This research builds an air flow and heat transfer model of a cold room (5.75 m × 3.

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Intuition suggests that passage times across a region increase with the number of barriers along the path. Can this fail depending on the nature of the barrier? To probe this fundamental question, we exactly solve for the first passage time in general -dimensions for diffusive transport through a spatially patterned array of obstacles - either entropic or energetic, depending on the nature of the obstacles. For energetic barriers, we show that first passage times vary non-monotonically with the number of barriers, while for entropic barriers it increases monotonically.

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Article Synopsis
  • Activation-induced cytidine deaminase (AID) triggers somatic hypermutation and class-switch recombination, which are key for creating effective, pathogen-specific antibodies.
  • The accessibility of chromatin influences AID's expression and activity, with chromatin remodelers playing a crucial role in enabling AID to target immunoglobulin (Ig) genes.
  • Epigenetic modifications, such as DNA methylation and histone changes, significantly affect AID regulation and its targeting, forming a complex interplay known as the ACE phenomenon, which is vital for potential therapeutic advancements.
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