Publications by authors named "M Darby"

Introduction: Low dose CT (LDCT) screening for lung cancer reduces lung cancer mortality, but there is a lack of international consensus regarding the optimal eligibility criteria for screening. The Yorkshire Lung Screening Trial (YLST) was designed to evaluate lung cancer screening (LCS) implementation and a primary objective was prospective evaluation of 3 pre-defined eligibility criteria.

Methods: Individuals who had ever smoked, aged 55-80yrs, who responded to written invitation, underwent telephone risk assessment and if eligible by at least one criteria (PLCO≥1.

View Article and Find Full Text PDF

Lack of access to primary care contributes to health inequities. Treatment settings that utilize the full experience and training of nurses, both registered nurses (RNs) and advanced practice registered nurses (APRNs), can expand in primary care and successfully address health inequities. This small study describes the implementation of a model of primary care called intensive primary care (IPC), which has eight elements that support the full utilization of a nurse's experience and training.

View Article and Find Full Text PDF

Objectives: To evaluate radiation doses for all low-dose CT scans performed during the first year of a lung screening trial.

Methods: For all lung screening scans that were performed using a CT protocol that delivered image quality meeting the RSNA QIBA criteria, radiation dose metrics, participant height, weight, gender, and age were recorded. Values of volume CT dose index (CTDIvol) and dose length product (DLP) were evaluated as a function of weight in order to assess the performance of the scan protocol across the participant cohort.

View Article and Find Full Text PDF
Article Synopsis
  • The study explored how financial difficulties (financial toxicity) affect patients undergoing evaluation for hematopoietic cell transplantation (HCT) and their post-transplant quality of life.
  • Out of 245 participants, a significant number (around 53%) reported mild to moderate-high financial toxicity, with many resorting to cost-cutting measures affecting their health and lifestyle.
  • Factors such as older age and higher income were linked to lower levels of financial toxicity, while those experiencing moderate-high toxicity reported poorer quality of life six months to a year after the transplant.
View Article and Find Full Text PDF

Objective: As lung cancer screening is rolled-out, there is a need to develop an effective quality assurance (QA) framework around radiology reporting to ensure optimal implementation. Here, we report a structured QA process for low-dose CT (LDCT) scans performed in the Yorkshire Lung Screening Trial.

Methods: Negative LDCT scans were single read after using computer-aided detection software.

View Article and Find Full Text PDF