The place of S-ketamine in fibromyalgia treatment (ESKEFIB): study protocol for a prospective, single-center, double-blind, randomized, parallel-group, dose-escalation controlled trial.

Background: Fibromyalgia is a chronic multidimensional pain disease with no curative treatment currently available. Its management relies on a multimodal approach involving pharmacologic and non-pharmacologic elements. Because a suggested factor in its etiology is a central sensitization phenomenon involving the N-methyl-D-aspartate receptor (NMDAR), NMDAR antagonists have been proposed as a treatment target.

Tracheal perforation following double-lumen intubation: a case report.

Tracheal perforation following endotracheal intubation is an underestimated complication that seriously compromises prognosis. Treatment can be either conservative or surgical, depending on the lesion and the patient's clinical condition. In this case report, we describe a patient in whom tracheal perforation occurred during double-lumen tube placement for elective surgery on a pulmonary nodule.

Connection error in the delivery of medical gases to a surgical unit.

Whilst anesthetic incidents due to problems with the delivery of medical gases to a surgical unit are exceptional, their consequences are potentially drastic. With the growing of modern hospitals, every anesthetist may one day find himself confronted with such events, which are new to him, partly because they are infrequent, but mainly because they are due to causes outside his immediate environment. A simple mistake in the labelling and identification of medical gas lines resulted in a cross-connection of the oxygen and air, causing perioperative hypoxemia following the administration of a mixture poor in oxygen.