Biological Amyloids Chemically Damage DNA.

Amyloid fibrils are protein polymers noncovalently assembled through β-strands arranged in a cross-β structure. Biological amyloids were considered chemically inert until we and others recently demonstrated their ability to catalyze chemical reactions in vitro. To further explore the functional repertoire of amyloids, we here probe if fibrils of α-synuclein (αS) display chemical reactivity toward DNA.

Experiences Using Media Health Claims to Teach Evidence-Based Practice to Healthcare Students: A Mixed Methods Study.

Background: A multifaceted and interactive teaching approach is recommended for achieving proficiency in evidence-based practice, with critical thinking considered vital for connecting theory and practice. In this context, we advocate the strategic use of health claims in the media to promote critical thinking, complemented by a blended learning approach and a group exam.

Method: We conducted a convergent mixed methods study, including a cross-sectional survey with structured and open-ended questions as well as focus group interviews, at Oslo Metropolitan University, during the 2020-2021 academic year.

Chlorella and vegetable oil inclusion in diets for growing rabbits: effects on growth, digestibility, plasma metabolites, and caecal fermentations and microbiota.

The inclusion of microalgae in livestock diets has been shown to enhance animal productivity, immune response, and meat quality. However, the role of chlorella (Chlorella vulgaris) in growing rabbit nutrition has been scarcely explored, with available studies focusing on low inclusion levels (<1%) and their effects on rabbit growth and immune response. This study evaluated the growth performance, nutrient digestibility, plasma metabolites, caecal fermentative activity, and caecal microbiota composition of growing rabbits fed diets with different inclusion levels of chlorella and crude fat.