Progressive postoperative atrophy of ipsilateral thalamus, putamen, and globus pallidus in patients with temporal lobe epilepsy: A volumetric analysis.

Objective: Cortical atrophy close to medial temporal structures has been described consistently in patients with temporal lobe epilepsy (TLE). Successful TLE surgery may have a neuroprotective effect preventing further atrophy of temporal and extratemporal cortex. However, the effects of epilepsy surgery on subcortical structures demand additional enlightenment.

Subsegmentation of the hippocampus in subgroups of migraine with aura patients: advanced structural neuroimaging study.

Background: This study investigated for a possible contributing role of hippocampus in the different clinical phenotypic manifestations of migraine aura.

Methods: Herein, patients were categorized as those with pure visual aura (MwAv), those who reported additional somatosensory and dysphasic symptoms (MwAvsd), and healthy controls (HCs). Neuroimaging data obtained using FreeSurfer-based segmentation of hippocampal subfields were compared between HCs and patients with migraine with aura, as well as between HCs and those with MwAv and MwAvsd.

Cluster-CAM: Cluster-weighted visual interpretation of CNNs' decision in image classification.

Despite the tremendous success of convolutional neural networks (CNNs) in computer vision, the mechanism of CNNs still lacks clear interpretation. Currently, class activation mapping (CAM), a famous visualization technique to interpret CNN's decision, has drawn increasing attention. Gradient-based CAMs are efficient, while the performance is heavily affected by gradient vanishing and exploding.

Exploring the Co-Crystallization Landscape of One-Dimensional Coordination Polymers Using a Molecular Electrostatic Potential-Driven Approach.

The ability of coordination polymers (CPs) to form multicomponent heteromeric materials, where the key structural features of the parent CP are retained, has been explored via molecular electrostatic potential-driven co-crystallization technologies. Thirteen co-formers presenting hydrogen-bond donors activated through a variety of electron-withdrawing functionalities were employed, and the extent of activation was evaluated using molecular electrostatic potential values. Attempted co-crystallizations of the seven most promising co-formers with a family of nine CPs ([CdX'(X-pz)]; X' = I, Br, and Cl; X = I, Br, and Cl) resulted in six successful outcomes; all four of the structurally characterized compounds displayed the intended hydrogen bond.