Publications by authors named "M Dacey"

Objective: To obtain physicians' "real-world" perspectives on early experiences with triamcinolone acetonide suprachoroidal injection (SCS-TA) for treatment of patients with uveitic macular edema (UME).

Results: Twelve retina/uveitis specialists in the United States were surveyed about SCS-TA injection procedure and patient outcomes. Survey participants administered ≥ 291 SCS-TA injections to 243 patients with UME with various disease characteristics (etiologies, chronicity, and anatomical subtypes).

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Article Synopsis
  • - Noninfectious uveitis is a major cause of vision loss and there is a need for better treatment options, prompting the investigation of filgotinib, a JAK1 inhibitor, for this condition.
  • - The HUMBOLDT trial was a phase 2 study involving 74 participants, aged 18 and older, with active noninfectious uveitis, comparing filgotinib to a placebo over 52 weeks.
  • - Results showed that 37.5% of those on filgotinib experienced treatment failure by week 24, significantly lower than the 67.6% for placebo, indicating that filgotinib may be an effective option for treating this illness.
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Background: Lung transplant surgery creates surgical pulmonary vein isolation (PVI) as a routine part of the procedure. However, many patients with pretransplant atrial fibrillation continue to have atrial fibrillation at 1 y. We hypothesized that the addition of electrical PVI and left atrial appendage isolation/ligation (LAL) to the lung transplant procedure restores sinus rhythm at 1 y in patients with pretransplant atrial fibrillation.

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Background: Ex-situ lung perfusion (ESLP) can be used to assess and rehabilitate donor lungs, potentially expanding the donor pool. We examined the characteristics and outcomes of lung transplants performed with ESLP in the United States.

Methods: Retrospective review of the United Network for Organ Sharing registry of primary adult lung transplant recipients from February 28, 2018, to June 30, 2021, was performed, comparing baseline characteristics, in-hospital outcomes, and 1-year survival of ESLP vs no ESLP lung transplants.

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It has long been recognized that humans tend to anthropomorphize. That is, we naturally and effortlessly interpret the behaviors of nonhuman agents in the same way we interpret human behaviors. This tendency has only recently become a subject of empirical research.

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