Publications by authors named "M DEL VECCHIO"
Article Synopsis
- Pineal cysts are benign growths in the pineal gland often found accidentally during MRIs, usually causing no symptoms but can lead to neurological issues if they grow.
- The exact causes of these cysts are unclear, but factors like inflammation from conditions like fibromyalgia and mechanical stress may contribute, along with potential links to long-term lithium use in psychiatric treatment.
- A case study of a 49-year-old woman with bipolar disorder on lithium highlighted possible connections between cyst formation, systemic inflammation, and psychiatric conditions, indicating the need for more research on these interactions.
SERPINA3, a serine protease inhibitor, is strongly associated with neuroinflammation, a typical condition of AD. Its expression is linked to microglial and astrocytic markers, suggesting it plays a significant role in modulating neuroinflammatory responses. In this study, we examined the SERPINA3 expression levels, along with CHI3L1, in various brain regions of AD patients and non-demented healthy controls (NDHC).
View Article and Find Full Text PDF: Dabrafenib and trametinib (D + T) have been approved for the treatment of stage III melanoma with BRAF V600E V600K mutations in an adjuvant setting, based on the results from the COMBI-AD trial. To provide early access to this combination therapy prior to its commercial availability in Italy, a Managed Access Program (MAP) was run in Italy from June 2018 to December 2019. : The MADAM (Maximing ADjuvAnt MAP) study is an Italian retrospective-prospective observational study that included patients who received at least one dose of D + T through the MAP.
View Article and Find Full Text PDF: Mastocytosis (MS) is a rare disease that can involve various organs, including the bone. Given the incidence of the disease in the global population, MS poses a challenge for physicians, and early therapeutic intervention in the initial stages could significantly impact the quality of life of affected patients. : The aim of this scoping review was to provide an overview of secondary osteoporosis in systemic mastocytosis (SM), focusing on the heterogeneity of its manifestations, the benefits of early diagnosis, and appropriate pharmacological treatment.
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