Status Quo of Mental Health and Influencing Factors Among Older Adults in Different Living Situations: A Random Forest Analysis Based on CHARLS Data.

Purpose: To determine the status of depression and its key influencing factors among Chinese older adults in different living situations.

Method: Data of 7,092 older adults were obtained from the China Health and Retirement Longitudinal Survey. This study analyzed key variables influencing depressive symptoms using random forest modeling and logistic regression.

Platelet membrane-modified exosomes targeting plaques to activate autophagy in vascular smooth muscle cells for atherosclerotic therapy.

Atherosclerosis is one of the leading causes of ischemic cardiovascular disease worldwide. Recent studies indicated that vascular smooth muscle cells (VSMCs) play an indispensable role in the progression of atherosclerosis. Exosomes derived from mesenchymal stem cells (MSCs) have demonstrated promising clinical applications in the treatment of atherosclerosis.

Nanoclay-Mediated Crystal-Phase Engineering in Biofunctions to Balance Antibacteriality and Cytotoxicity.

The crystalline phase of metal oxides is a key determinant of the properties and functions of the nanomaterials. Traditional approaches have focused on replicating bulk-phase structures, with limited exploration of phase diversity due to challenges in controlling the crystal morphology. Here, we introduce a nanoclay-mediated strategy for crystal-phase engineering, using talc to modulate the morphology and phase of manganese oxide (MnOx) nanoparticles.

Home visiting for postpartum depression.

This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To assess the benefits of home visiting models for postpartum depression amongst mothers of young children, where either the mothers or the children are enrolled in early childhood home visiting programs or interventions. To identify core components essential for a home visiting program to effectively address postpartum depression in mothers of young children.

Relationships between orofacial pain and sleep: Analysis of UK biobank and genome-wide association studies data.

Background/purpose: Orofacial pain is common in dental practices. This study aimed to explore relationships between orofacial pain and sleep using the UK Biobank dataset and, based on epidemiological associations, to investigate the causal association using genome-wide association studies data.

Materials And Methods: First, a cross-sectional study was conducted with 196,490 participants from UK Biobank.