Publications by authors named "M D Schluter"
Background Transjugular intrahepatic portosystemic shunt (TIPS) dysfunction in patients with liver cirrhosis and recurrent symptoms of portal hypertension is primarily assessed with US and confirmed with invasive catheter venography, which can be used to measure the portosystemic pressure gradient (PSPG) to identify TIPS-refractory portal hypertension. To avoid the risks and costs of invasive catheter venography, noninvasive PSPG evaluation strategies are needed. Purpose To demonstrate the feasibility of the combination of four-dimensional (4D) flow MRI with computational fluid dynamics (CFD) for noninvasive PSPG assessment in participants with cirrhosis and TIPS.
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- Crop booms refer to sudden and intense expansions of specific crops, but they are unpredictable and difficult to control.
- This study uses complex systems theory to analyze the dynamics of crop booms, particularly focusing on rubber and banana plantations in northern Laos.
- Key factors influencing these booms include previous agricultural trends, policy and market changes, and internal feedback mechanisms that create self-reinforcing behaviors, which help define the growth patterns and thresholds of these crop expansions.
When reasoning about causes of sustainability problems and possible solutions, sustainability scientists rely on disciplinary-based understanding of cause-effect relations. These disciplinary assumptions enable and constrain how causal knowledge is generated, yet they are rarely made explicit. In a multidisciplinary field like sustainability science, lack of understanding differences in causal reasoning impedes our ability to address complex sustainability problems.
View Article and Find Full Text PDFDuring the scale-up of biopharmaceutical production processes, insufficiently predictable performance losses may occur alongside gradients and heterogeneities. To overcome such performance losses, tools are required to explain, predict, and ultimately prohibit inconsistencies between laboratory and commercial scale. In this work, we performed CHO fed-batch cultivations in the single multicompartment bioreactor (SMCB), a new scale-down reactor system that offers new access to study large-scale heterogeneities in mammalian cell cultures.
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- Human activities are changing the Earth quickly, and this is causing big problems for sustainability.
- Researchers are studying how people and the environment interact to figure out how to make things better in the future.
- This paper talks about combining ideas from biology (evolutionary theory) with social-ecological research to understand these changes better and find ways to improve our world.