Smile Reestablished-Predictable Management of Complicated Crown-root Fracture through Surgical Extrusion with and without 180° Rotation: A Case Report.

Aim And Background: The management of crown-root fractures poses significant uncertainty and involves meticulous evaluation of the tooth and supporting structures. The uncertain prognosis associated with crown-root fractures necessitates periodic evaluation.

Case Description: A 15-year-old female presenting with crown-root fracture of the permanent left maxillary incisors was treated by surgical extrusion with rotation for the central incisor, while the lateral incisor was coronally extruded by 2 mm.

Recent advances in microfluidic chip technologies for applications as preclinical testing devices for the diagnosis and treatment of triple-negative breast cancers.

The leading cause of cancer-related death among female patients is breast cancer. Among all the types of breast cancer, triple-negative breast cancer (TNBC) is the most dangerous molecular subtype of breast cancer characterized by the absence of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER-2) expression. Since there is no particular therapeutic strategy for TNBC that has been shown to worsen the disease prognosis, 3D models are superior to 2D models as a predictive tool for drug discovery because they more accurately reflect the in vivo biological components of humans.

Mapping changes in the utilization of childhood immunization over 5 years in a south Indian tertiary care hospital.

Background: Altered vaccine demands and uneven utilization patterns in childhood immunization are evident nationwide. These variabilities may stem from a range of internal and external factors influencing parental preferences. Regular checks and balances are necessary to ensure equal accessibility for all sections of society.

Assessment of Factors Associated with Mandibular Anterior Crowding in Mixed Dentition.

Introduction: Dental crowding can be defined as a disparity in the relationship between the tooth size and arch length, which results in imbrication and rotation of teeth. Crowding of permanent teeth, especially in the anterior part of the mandible, is believed to be the most frequent form of malocclusion in children. The appropriate age for treatment of crowding is the late mixed dentition period.