Publications by authors named "M D Poleti"

Background: Advancements in metabolomic technologies have revolutionized our understanding of feed efficiency (FE) in livestock, offering new pathways to enhance both profitability and sustainability in ruminant production.

Methods: This review offers a critical and systematic evaluation of the metabolomics methods used to measure and assess FE in ruminants. We conducted a comprehensive search of PubMed, Web of Science, and Scopus databases, covering publications from 1971 to 2023.

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Different energy sources are often used in horse diets to enhance health and performance. Understanding how diet impacts the cecal and fecal microbiota is crucial for meeting the nutritional needs of horses. High-throughput sequencing and qPCR were used to compare the fecal and cecal microbiota of five healthy horses receiving three different diets: hay diet (HAY), hay + starch and sugar (SS), and hay + fiber and oil ingredients (FO).

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Article Synopsis
  • Since 2021, Brazil has faced a surge in COVID-19 cases and deaths due to new variants of concern (VOC) and low vaccination rates, which have led to the emergence of more mutations.
  • The study aimed to assess whether local genomic surveillance and epidemiological data can reflect nationwide trends in the COVID-19 pandemic.
  • Findings revealed three key variant replacements (Gamma, Delta, and Omicron) and highlighted that vaccination became increasingly effective in preventing new cases and deaths as the pandemic progressed.
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The aim of this study was to assess whether toothbrushing with a dentifrice containing an antimicrobial phthalocyanine derivative (APD) can reduce the intraoral viral load of SARS-CoV-2. Twenty COVID-19-positive dentate patients aged ≥18 years were selected instructed to brush their teeth for 2 min with a dentifrice containing APD. Self-collected samples of unstimulated saliva were carried out three times: T0 (baseline), T5 (5 min after toothbrushing), and T30 (30 min after toothbrushing).

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Article Synopsis
  • Metagenomics has evolved to analyze the ruminal microbiome, focusing on how it influences significant traits in animal production and the importance of mobile genetic elements (MGEs) in gene transfer and ecological balance.
  • The study used advanced techniques like Hi-C method and shotgun metagenomic sequencing to explore the relationships between ruminal bacteria and their MGEs in Nellore cattle, yielding over 1.7 billion base pairs and identifying key bacterial families.
  • The research found 31 associations between bacteria and MGEs, including links to viruses and antibiotic resistance genes, marking a first in Brazilian cattle and providing insights to enhance food digestion and ruminant productivity.
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