Publications by authors named "M D Plotkin"
Article Synopsis
- The study aimed to analyze brain structure differences in children with ADHD and those with obesity, focusing on brain regions related to cognitive control and reward.
- It involved 471 children aged 8-12, comparing brain morphology using structural MRI between those with ADHD (some being overweight/obese) and neurotypical controls (some also overweight/obese).
- Results showed lower surface area in ADHD children and lower cortical thickness in those with obesity, suggesting unique brain changes associated with each condition as well as combined effects of ADHD and obesity on brain regions important for cognitive and motivational processes.
Herpesvirus infections are ubiquitous, with over 95% of the adult population infected by at least one strain. While most of these infections resolve without treatment in healthy individuals, they can cause significant morbidity and mortality in immunocompromised, stem cell, or organ transplant patients. Current nucleoside standards of care provide meaningful benefit but are limited due to poor tolerability, resistance, and generally narrow spectrum of activity.
View Article and Find Full Text PDFBackground: As oral PrEP scales up in Nigeria, information about uptake, use pattern and client preference in a real-world, implementation setting is invaluable to guide refining service provision and incorporation of oral PrEP and other prevention measures into routine health services. To add to this body of knowledge, our study examines factors associated with discontinuation of PrEP among HIV negative individuals across two large scale programs in Nigeria.
Methods: Using program implementation data from two large-scale HIV projects in Akwa Ibom and Cross River states in Nigeria between January 2020 and July 2021, we used logistic regression to explore factors associated with early discontinuation (i.
Objective: To determine whether girls and boys with ADHD show distinct impairments in components of cognitive control across multiple tasks (go/no-go, stop signal, and flanker) and performance metrics (response speed, variability, and errors).
Method: A total of 300 children, ages 8 to 12 years with ADHD ( = 210, 58 girls) or typically developing (TD; = 99, 37 girls), completed all tasks. Traditional response measures (e.
Background: In Nigeria, in-service trainings for new family planning (FP) methods have typically been conducted using a combination of classroom-based learning, skills labs, and supervised practicums. This mixed-methods study evaluated the feasibility, acceptability, provider competency, and costs associated with a hybrid digital and in-person training model for the hormonal intrauterine device (IUD).
Methods: The study was conducted in Enugu, Kano, and Oyo states, Nigeria, and enrolled FP providers previously trained on non-hormonal IUDs.