Publications by authors named "M D Noseworthy"

Article Synopsis
  • Concussion, affecting about 1.2% of the population annually, poses a significant public health issue, particularly among children aged 1-17, who experience this injury more frequently than others.
  • The study focused on youth with concussions to evaluate adherence to Return to Activity (RTA) protocols, examining how this adherence impacts recovery time and the risk of reinjury.
  • Results showed low adherence to RTA protocols using accelerometers (13%-34% across stages), but subjective self-reports indicated better compliance, with adherent youths recovering faster (13 days) than non-adherent youths (20 days), despite discrepancies between self-reported and objective measures.
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Exercise and nature exposure are independently recognised for their positive relationship with health, but their combined effects are not fully understood. The present review summarises the evidence that compares physiological and perceptual differences of a single bout of exercise performed outdoors versus indoors. Nine databases were searched for articles published before March 2021 which utilised controlled designs to assess at least one physiological outcome during or after a single acute bout of outdoor exercise.

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Background: Recent scientific evidence has challenged the traditional "rest-is-best" approach for concussion management. It is now thought that "exercise-is-medicine" for concussion, owing to dozens of studies which demonstrate that sub-maximal, graded aerobic exercise can reduce symptom burden and time to symptom resolution. However, the primary neuropathology of concussion is altered functional brain activity.

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The MR-induced gradient artifact affects EMG recordings during simultaneous muscle BOLD/EMG acquisitions. However, no dedicated hardware can remove the gradient artifact easily, and alternative methods are expensive and time-consuming. This study aimed to develop three denoising methods requiring different processing levels and MR-compatible hardware.

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Article Synopsis
  • The study investigates how cerebral small vessel disease (SVD) and amyloid beta (Aβ) impact hippocampal atrophy, which affects memory in dementia.
  • Researchers examined a cohort with both Alzheimer's disease and SVD, assessing how SVD, white matter hyperintensities (WMH), and Aβ influence hippocampal volume and shape using advanced imaging techniques.
  • Findings indicate that frontal WMH and Aβ independently contribute to reduced hippocampal volume, while their effects on hippocampal shape vary, suggesting specific patterns of atrophy could help in diagnosing and treating mixed dementia.
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