Publications by authors named "M D Niembro-Ortega"
Histoplasmosis is an endemic and invasive mycosis caused by . We conducted a retrospective study comparing immunosuppressed patients without human immunodeficiency virus (HIV) with a historical cohort of people with HIV and histoplasmosis. We included 199 patients with proven or probable histoplasmosis, of which 25.
View Article and Find Full Text PDFDiagnostic accuracy of antigen detection in urine and molecular assays testing in different clinical samples for the diagnosis of progressive disseminated histoplasmosis in patients living with HIV/AIDS: A prospective multicenter study in Mexico.
PLoS Negl Trop Dis
March 2021
Article Synopsis
- A multicenter study in Mexico aimed to evaluate the effectiveness of various tests for diagnosing progressive disseminated histoplasmosis (PDH) in individuals living with HIV.
- The study involved 415 participants and compared the diagnostic accuracy of urine antigen tests and nested PCR methods, confirming PDH through blood, tissue cultures, or histopathology.
- Results showed that the cHGEI IMMY test had the highest sensitivity (91.3%) among the urine tests, while nested PCR tests demonstrated varying sensitivity levels, indicating different diagnostic strengths for identifying this serious infection.
Objectives: The aim of this study was to investigate the feasibility of saliva sampling as a non-invasive and safer tool to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and to compare its reproducibility and sensitivity with nasopharyngeal swab samples (NPS). The use of sample pools was also investigated.
Methods: A total of 2107 paired samples were collected from asymptomatic healthcare and office workers in Mexico City.
Introduction: Opsoclonus-myoclonus-ataxia (OMA) syndrome is a rare neurological disorder characterized by involuntary conjugate saccadic eye movements, myoclonus, and ataxia. Few reports exist on patients with HIV and OMA.
Case Report: A 41-year-old man diagnosed with HIV-1 infection in 1997 coursed with multiple anti-retroviral schemes as a consequence of poor adherence.
Latent Tuberculosis in Hematopoietic Stem Cell Transplantation: Diagnostic and Therapeutic Strategies to Prevent Disease Activation in an Endemic Population.
Biol Blood Marrow Transplant
July 2020
Latent tuberculosis infection (LTBI) affects one-fourth of the world´s population. Hematopoietic stem cell transplantation (HSCT) recipients are at an elevated risk of developing active tuberculosis infection (ATBI). In this retrospective study of donors and HSCT recipients who underwent transplantation between February 2000 and June 2018, our aim was to determine the prevalence of LTBI and ATBI and to describe diagnostic and therapeutic strategies in an HSCT population in an endemic region.
View Article and Find Full Text PDF