Publications by authors named "M D Marrodan"
Analysis of the International Index of Erectile Function: psychometric evidence and measurement invariance across relationship status and age generations in a Chilean sample.
Sex Med
December 2024
Background: The International Index of Erectile Function (IIEF) stands out for its utility and widespread use to measure sexual function in men. However, it lacks consistency in its internal latent structure across studies, has not been evaluated for measurement invariance, and has not undergone psychometric validation for its 15-item form in Spanish among South American countries.
Aim: To examine the IIEF's psychometric evidence (ie, structural/criterion validity and reliability) in a sample of adult men and determine its measurement invariance across relationship status (single vs in a relationship) and age generations (generations Z, Y/millennials, and X).
Live-attenuated vaccines provide robust immunity against diseases like tuberculosis, measles, mumps, rubella, polio, yellow fever, dengue, typhoid fever, and varicella, with just one or a few doses. However, concerns arise regarding potential pathogen reversion to virulence, which is particularly risky for immunocompromised individuals, contraindicating their administration in multiple sclerosis (MS) patients under modified disease treatments due to the possibility of triggering infections, or stimulating the immune system, precipitating new exacerbations. On the contrary, these vaccines offer enduring immunity that is crucial for protecting MS patients from endemic infectious diseases, leading to severe complications if contracted.
View Article and Find Full Text PDFBackground: Leukocyte telomere length (LTL) shortens with age and may be related to multiple sclerosis (MS).
Objective: We hypothesize that chronologically young people with MS (pwMS) with short LTL behave similarly to older MS subjects.
Methods: Prospective 2-year study including two cohorts of young (18-35 years) and elderly (⩾50 years) pwMS with similar disease duration.
Article Synopsis
- Susac syndrome, multiple sclerosis, and primary angiitis of the central nervous system often present similar symptoms, making accurate diagnosis a challenge; the study aimed to improve this through a new scoring system called the SPAMS score.
- The research involved 99 patients from South America and utilized an elastic-net model to determine important MRI features for distinguishing between these conditions.
- The SPAMS score demonstrated high diagnostic accuracy, effectively differentiating SuS from MS and PACNS, highlighting the importance of specific MRI findings for timely interventions and potentially better patient outcomes.